Propionibacterium acnes is associated with Acne vulgaris (pimples), but it is not the sole cause of it. Propionibacterium acnes is a Gram positive, non-spore forming, anaerobic pleomorphic bacillus found in clinical specimens. The morphology and arrangement of Propionibacterium acnes is similar to that of Corneybacterium, but is non-toxigenic. Propionibacterium acnes is normal flora but ferments glucose leading to the production of propionic acid. It can also produce catalase along with indole, nitrate, or both indole and nitrate ("Propionibacterium acnes3").
Being an anaerobe, one might think that this bacterium would be more common in the intestines or tissues that are normally not exposed to the open air. However, this is not the case. Propionibacterium acnes loves air-exposed areas and is common around the nose and face. Even though it grows as an obligate anaerobe, Propionibacterium acnes survives in these areas because it lives in the sealed chamber-like habitats of sebaceous follicles.
Sebaceous follicles are glands in the skin attached to hair follicles located in the face, neck, back, and chest. These glands produce a substance called sebum. It is this oily substance on which the Propionibacterium acnes feeds. The sebum along with hair follicles and dead cells contribute to the sealing of the hair follicle to allow these bacteria to grow anaerobically. Within the sebaceous follicles, the sebum mixes with shed cells causing overgrowth of Propionibacterium acnes. The bacteria release lipases in order to digest the great amount of sebum that has been produced. The digest products (fatty acids) combine with bacterial antigens to create an inflammation causing the hair follicle to erupt. The bursting of the follicle leads to the lesions or pimples that are characteristic of acne ("Organisms Associated with Skin Defects and Diseases10").
Pathogenicity and Disease Symptoms
Acne is one of the most...
available respondents and fitted to the study (because almost of the students suffered and aresuffering from acne). The needed data were completed and had been validated.The copies of the questionnaire were distributed personally by the researcher to therespondents. Just after a few minutes, all the copies distributed were retrieved also personally bythe researcher.
Facts and Myths about the Causes of AcneFactsMyths1.Stress1. Heredity with the exception of verysevere acne.2.Hormones (especially duringmenstruation)2. Food like pizza, chocolates, junk foods,greasy and fried foods.3.Oil-based make up, suntan oil andhair products.4.Cosmetics that are water based and oilfree skin care products.5.Hard Scrubbing of the Skin6.Pressure from helmets, chinstraps,collars and suspenders.7.Drugs because some medication canworsen acne.8.Occupations that is exposed toindustrial products like cutting oils.9.Squeezing or picking at blemishes.10.Environmental Irritants.
Table 1.1 Facts and myths about the causes of acne
The researchers conducted a survey on what age does acne occur on teenagers. Theresearchers have given this survey to 34 students in 4
year high school. And the results can beseen on table 1.2.